Malaria Chloroquine Phosphate
Chloroquine can be used for preventing malaria from Plasmodium vivax, P. ovale, and P. malariae. Popular drugs based on chloroquine phosphate (also called nivaquine) are Chloroquine FNA, Resochin, and Dawaquin. Many areas of the world have widespread strains of chloroquine-resistant P. falciparum, so other antimalarials, such as mefloquine or atovaquone, may be advisable instead. Combining chloroquine with proguanil may be more effective against chloroquine-resistant P. falciparum than treatment with chloroquine alone, but is no longer recommended by the Centers for Disease Control and Prevention due to the availability of more effective combinations. For children 14 years of age or below, the dose of chloroquine is 600 mg per week. Contact the doctor for correct dosage!
Chloroquine 10 tablets.
- Chloroquine has long been used in the treatment or prevention of malaria. After the malaria parasite Plasmodium falciparum started to develop widespread resistance to it, new potential uses of this cheap and widely available drug have been investigated. Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance.
- In treatment of amoebic liver abscess, chloroquine phosphate may be substituted or added in the event of failure of resolution of clinical symptoms with metronidazole or another nitroimidazole within 5 days or intolerance to metronidazole or a nitroimidazole.
- As it mildly suppresses the immune system, it is used in some autoimmune disorders, such as rheumatoid arthritis and lupus erythematosus.
- Chloroquine is in clinical trials as an investigational antiretroviral in humans with HIV-1/AIDS and as a potential antiviral agent against chikungunya fever.
- The radiosensitizing and chemosensitizing properties of chloroquine are beginning to be exploited in anticancer strategies in humans.
- In biomedicinal science, chloroquine is used for in vitro experiments to inhibit lysosomal degradation of protein products.
Against rheumatoid arthritis, it operates by inhibiting lymphocyte proliferation, phospholipase A2, antigen presentation in dendritic cells, release of enzymes from lysosomes, release of reactive oxygen species from macrophages, and production of IL-1.
|Chloroquine Phosphate 250 mg||
Purchase of 10 tablets. Adult the first day 4 tablets (1g.)immediately, then 2 tablets (500mg.) after 6 to 8 hours; on the second and third days 1 tablet two times a day after meals. Children: 4-6 years 1 tablet 2 times a day , 7-8 years or upwards 2 tablets 2 times a day or as directed by the physician. Contact the doctor for advice and correct dosage !